i1- Wich of th following is not a major pathway or type of biotransformations ?i
a- Oxidation
b- Deamination
c- Reduction
d- Hydrolysis
e- Conjugation
a- Oxidation
b- Deamination
c- Reduction
d- Hydrolysis
e- Conjugation
i2- Which of the following is not a naturally occurring emulsifier?i
a- Acacia
b- Cholesterol
c- Gelatine
d- Veegum
e- Tragacanth
a- Acacia
b- Cholesterol
c- Gelatine
d- Veegum
e- Tragacanth
i3- Which of the following symptoms is not present in digitalis intoxication?i
a- AV block
b- Ventricular tachycardia
c- Vomiting
d- Vagal arrest of the heart
e- Visual disturbances
a- AV block
b- Ventricular tachycardia
c- Vomiting
d- Vagal arrest of the heart
e- Visual disturbances
i4- Which of the following statements about propylthiouracil is false ?i
a- It is used for treatment of hyperthyroidism
b- It inhibits the synthesis of thyroid hormones
c- It diminishes peripheral deiodination of T4 and T3
d- It inhibits iodide oxidation
e- It interferes with the effectiveness of exogenously administered thyroid hormones
a- It is used for treatment of hyperthyroidism
b- It inhibits the synthesis of thyroid hormones
c- It diminishes peripheral deiodination of T4 and T3
d- It inhibits iodide oxidation
e- It interferes with the effectiveness of exogenously administered thyroid hormones
i5- All of the following are diuretics except :i
a- Aminophylline
b- Glyburide
c- Spironolactone
d- Bum etamide
e- Chlorthalidone
a- Aminophylline
b- Glyburide
c- Spironolactone
d- Bum etamide
e- Chlorthalidone
i6- Which of the following is not a side effect of codeine?i
a- Miosis
b- Nausea
c- Diarrhea
d- Respiratory depression
e- Addiction
a- Miosis
b- Nausea
c- Diarrhea
d- Respiratory depression
e- Addiction
i7- All of the following are natural estrogens or congeners except :i
a- Estradiol
b- Diethylstilbestrol
c- Estrone
d- Ethinyl estradiol
e- Estropipate
a- Estradiol
b- Diethylstilbestrol
c- Estrone
d- Ethinyl estradiol
e- Estropipate
i8- Epinephrine is not given orally because :i
a- It is inactivated in the gastric mucosa
b- Local vasoconstriction inhibits absorption
c- It is raoidly inactivated in circulation
d- None of the above
e- All of the above
a- It is inactivated in the gastric mucosa
b- Local vasoconstriction inhibits absorption
c- It is raoidly inactivated in circulation
d- None of the above
e- All of the above
i9- Wich of the following cardiac glycosides does not occur naturally ?i
a- Dogoxin
b- Oubain
c- Digitoxin
d- Amrinone
e- Nitroglycerin
a- Dogoxin
b- Oubain
c- Digitoxin
d- Amrinone
e- Nitroglycerin
i10- Various opiates may be used as all of the following except :i
a- Analgesics
b- Anti-inflammatories
c- Antidiarreals
d- Aids to anesthesia
e- Antitussive
a- Analgesics
b- Anti-inflammatories
c- Antidiarreals
d- Aids to anesthesia
e- Antitussive
i11- Which of the following is not a stimulant laxative ?i
a- Cascara Sagrada
b- Senna
c- Caster oil
d- Bisacodyl
e- Docsate
a- Cascara Sagrada
b- Senna
c- Caster oil
d- Bisacodyl
e- Docsate
i12- Which of the following action is not seen with sympathomimetics ?i
a- Pupil constriction
b- Increased heart rate
c- Sweat gland stimulation
d- Bronchiole dilation
e- Systemic blood vessel constriction
a- Pupil constriction
b- Increased heart rate
c- Sweat gland stimulation
d- Bronchiole dilation
e- Systemic blood vessel constriction
i13- All of the following statements about propranolol are true except :i
a- The oral route of administration is preferred
b- Propranolol penetratesin to the CNS
c- Propranolol is primarily biotransformed in the liver
d- Propranolol causes rashes and sore throut
e- It is non selective alpha antagonist
a- The oral route of administration is preferred
b- Propranolol penetratesin to the CNS
c- Propranolol is primarily biotransformed in the liver
d- Propranolol causes rashes and sore throut
e- It is non selective alpha antagonist
i14- Which of the following drugs is not a proton pump inhibitor ?i
a- Pantoprazole
b- Rabeprazole
c- Lansoprazole
d- Sulfisoxazole
e- Omeprazole
a- Pantoprazole
b- Rabeprazole
c- Lansoprazole
d- Sulfisoxazole
e- Omeprazole
i15- All of the following are side effects of progestins except :i
a- Weight gain
b- Headache
c- Fatigue
d- Constipation
e- Nausea and vomiting
a- Weight gain
b- Headache
c- Fatigue
d- Constipation
e- Nausea and vomiting
i16-Bacitarcin is not usually given parenterally because of its :i
a- Insolubility
b- Lack of stability
c- Pain at the injection site
d- Lack of potency
e- Nephrotoxicity
a- Insolubility
b- Lack of stability
c- Pain at the injection site
d- Lack of potency
e- Nephrotoxicity
i17- Which of the following drugs should not be administered with high fat meals ?i
i|. Indinazir
i||. Riluzole
i|||. Stavudine
i|. Indinazir
i||. Riluzole
i|||. Stavudine
a- | only
b- ||| only
c- | and || only
d- || and ||| only
e- | , || and |||i
b- ||| only
c- | and || only
d- || and ||| only
e- | , || and |||i
i18- Each of the following exert antimicrobial action by inhibiting cell wall synthesis except :i
a- Cephalosporins
b- Penicillin
c- Bacitracin
d- Vancomycin
e- Novobiocin
a- Cephalosporins
b- Penicillin
c- Bacitracin
d- Vancomycin
e- Novobiocin
i19- Which of the following antibiotics or group of antibiotics does not act by inhibiting of cell membrane function ?i
a- Erythromycin
b- Amphotericin B
c- Colistin
d- Nystatin
e- Polymyxins
a- Erythromycin
b- Amphotericin B
c- Colistin
d- Nystatin
e- Polymyxins
i20-Which of the following diuretics do not cause potassium loss ?i
a- Furosemide
b- Chlorthalidone
c- Triamterene
d- Hydrochlorothiazide
e- Metolazole
a- Furosemide
b- Chlorthalidone
c- Triamterene
d- Hydrochlorothiazide
e- Metolazole
i21- Which is not essential amino acid ?i
a- Threonine
b- Tryptophane
c- Glutamone
d- Methionine
a- Threonine
b- Tryptophane
c- Glutamone
d- Methionine
i22- Hypercalcemia does not occur in normal individuals because :i
a- Calcium is rapidly excreted
b- Calcium is rapidly biotransformed
c- Calcium is insoluble
d- Excess calcium is not absorbed
a- Calcium is rapidly excreted
b- Calcium is rapidly biotransformed
c- Calcium is insoluble
d- Excess calcium is not absorbed
i23- All of the following are true of haemolytic jaundice except :i
a- There is increased production of Bilirubin
b- Urobilinogin concentration is increased in urine
c- Production of Urobilinogin is increased
d- Bilirubin is found in the urine of the patient
e- None of the above because all are true
a- There is increased production of Bilirubin
b- Urobilinogin concentration is increased in urine
c- Production of Urobilinogin is increased
d- Bilirubin is found in the urine of the patient
e- None of the above because all are true
i24- Which of the following beta-adrenergic agents is not short acting ?i
a- Pirbuterol
b- Salmetrol
c- Terbutaline
d- Albuterol
e- None of the above
a- Pirbuterol
b- Salmetrol
c- Terbutaline
d- Albuterol
e- None of the above
i25- Possible treatment of Hypoglycemia does not include :i
a- Insulin
b- Candy
c- Glucose
d- Fruit juce
e- Glucagon
a- Insulin
b- Candy
c- Glucose
d- Fruit juce
e- Glucagon
i26- Which of the following Antihypertensive agents has no adverse effect on Glucose tolerance?i
i1-metoprolol
i2-atenolol
i3-captopril
i1-metoprolol
i2-atenolol
i3-captopril
ia. 1 only
ib. 3 only
ic. 1 and 2i
id. 2 and 3i
ie. 1 , 2 and 3 i
ib. 3 only
ic. 1 and 2i
id. 2 and 3i
ie. 1 , 2 and 3 i
i27- Signs and symptoms of acute Otitis media do not include :i
a- Fever
b- Irritability
c- Stuff neck
d- Lethargy
e- The child may be as asymptomatic
a- Fever
b- Irritability
c- Stuff neck
d- Lethargy
e- The child may be as asymptomatic
i28- Alternative Antibiotics for Otitis media for the child allergic to Penicillin include all of the following except :i
a- Clindamycin
b- Erythromycin
c- Erythromycin – Sulfisoxazole
d- Ciprofloxacin
e- Trimethoprin – Sulfamethoxazole
a- Clindamycin
b- Erythromycin
c- Erythromycin – Sulfisoxazole
d- Ciprofloxacin
e- Trimethoprin – Sulfamethoxazole
i29- It is important that the patient recognizes all the following signs as possible Lithium side effects except :i
a- Hand tremors
b- Headaches
c- Mudcle weakness
d- Constipation
e- Polyuria
a- Hand tremors
b- Headaches
c- Mudcle weakness
d- Constipation
e- Polyuria
i30- Which of the following is not useful in the treatment of acute Digoxin toxicity ?i
i1- calcium administration
i2- lidocaine administration
i3- fab fragment antibodies
i1- calcium administration
i2- lidocaine administration
i3- fab fragment antibodies
ia. 1 only
ib. 3only
ic. 1 and 2 only
id. 2 and 3 only
ie. 1 , 2 and 3
ib. 3only
ic. 1 and 2 only
id. 2 and 3 only
ie. 1 , 2 and 3
i31- Some common patient complaints associated with Anticholinergic drugs include all of the following except :i
a- Urinary retention
b- Sgortness of breath
c- Blurred vision
d- Constipation
e- Dry mouth
i32- Which of the following iron preparations is not available oral dosage form ?i
a- Iron drxtran
b- Ferrous fumarate
c- Ferrous gluconate
d- Ferrous sulphate
e- Polysaccharide – Iron complex
i33- In which of the following conditions is iron supplementation indicated ?i
i1 Primary hemochromatosis
i2 Patient receiving multiple blood transfusions
i3 Pregnancy
i1 Primary hemochromatosis
i2 Patient receiving multiple blood transfusions
i3 Pregnancy
a- 1 only
b- 3 Only
c- 1 and 2 only
d- 1, 2 and 3
b- 3 Only
c- 1 and 2 only
d- 1, 2 and 3
i34- Some symptoms of iron deficiency include all of the following except :i
a- Fatigue
b- Constant thirst
c- Dystrophy of nails
d- Dysphagia
e- Dispnea on exertion
a- Fatigue
b- Constant thirst
c- Dystrophy of nails
d- Dysphagia
e- Dispnea on exertion
i35- Which of the following agents would not be indicated for a patient with angina ?i
a- Isosorbide
b- Flecainide
c- Nifedipine
d- Inderal
e- Diltiazem
a- Isosorbide
b- Flecainide
c- Nifedipine
d- Inderal
e- Diltiazem
i36- All of the following may be symptoms of a myocardial infarction except :i
a- Myalgia, Mydriasis and Nocturia
b- Agitated behavior and ahen pallor
c- Nausea, sweating and dyspnea
d- Heartburn, fainting and skipped beats
e- Dental and neck pain, no relief from Nitroglycerin
a- Myalgia, Mydriasis and Nocturia
b- Agitated behavior and ahen pallor
c- Nausea, sweating and dyspnea
d- Heartburn, fainting and skipped beats
e- Dental and neck pain, no relief from Nitroglycerin
i37- All of the following are true about morphine except :i
a- May cause diarhoea
b- A m etabolite of codeine
c- Has specific receptors in the GIT
d- May cause vomiting
a- May cause diarhoea
b- A m etabolite of codeine
c- Has specific receptors in the GIT
d- May cause vomiting
i38- Which one of the following drugs is not available as antipsychotic depot injection ?i
a- Flupenthixol
b- Fluphenazine
c- Chlorpromazine HCL
d- Haloperidol Decanoate
a- Flupenthixol
b- Fluphenazine
c- Chlorpromazine HCL
d- Haloperidol Decanoate
i39- Which one of the following statements about chloral hydrate is false ?i
a- May cause gastritis
b- Can cause tolerance
c- It is a respiratory stimulant
d- Toxicity is much increased by administration of Ethanol
a- May cause gastritis
b- Can cause tolerance
c- It is a respiratory stimulant
d- Toxicity is much increased by administration of Ethanol
i40- Which one of the following statements about narcotic analgesics is false ?i
a- Codeine is useful for its anti tussive properties
b- Pentazocine is more addictive than morphine
c- Pentazocine may cause hallucinations
d- Morphine can cause diarhoea
a- Codeine is useful for its anti tussive properties
b- Pentazocine is more addictive than morphine
c- Pentazocine may cause hallucinations
d- Morphine can cause diarhoea
i41- Which of the following should not be used to prevent migraine in an asthmatic patient ?i
a- Propranolol (Inderal)i
b- Pizotifen (Sanomigran)i
c- Amitryptyline (Tryptizol)i
d- Clonidine (Dixarit)i
a- Propranolol (Inderal)i
b- Pizotifen (Sanomigran)i
c- Amitryptyline (Tryptizol)i
d- Clonidine (Dixarit)i
i42- Which of the following is not a benzodiazepine ?i
a- Alprazolam
b- Clobazem
c- Chlormethiazole
d- Chlordiazepoxide
a- Alprazolam
b- Clobazem
c- Chlormethiazole
d- Chlordiazepoxide
i43- Which of the following is true about Benzodiazepines ?i
a- Patients can develop a psychological dependence
b- Patients can develop a withdrawal syndrome
c- Patients can develop tolerance to the drug
d- All of the above
a- Patients can develop a psychological dependence
b- Patients can develop a withdrawal syndrome
c- Patients can develop tolerance to the drug
d- All of the above
i44- Dopamine tablets cannot be used to treat Parkinson’s disease because it :i
a- Does not cross blood brain barrier
b- Is too toxic after long term administration
c- Is transformed to L-dopa by the autonomic neurons
d- Is not m etabolized by mono amine oxidase
a- Does not cross blood brain barrier
b- Is too toxic after long term administration
c- Is transformed to L-dopa by the autonomic neurons
d- Is not m etabolized by mono amine oxidase
i45- Which of the following drugs cause insomnia ?i
a- MAOI’s
b- Caffeine
c- Beta blockers
d- Barbiturates
e- a, b and c
a- MAOI’s
b- Caffeine
c- Beta blockers
d- Barbiturates
e- a, b and c
i46- Which of the following is not effective for partial seizures ?i
a- Phenytoin
b- Ethosuximide
c- Carbamazepine
d- Lamotrigine
a- Phenytoin
b- Ethosuximide
c- Carbamazepine
d- Lamotrigine
i47- Amitryptyline causes all of the following except :i
a- Hypotension in the elderly
b- Raising of the seizure threshold
c- Sedation
d- Constipation
a- Hypotension in the elderly
b- Raising of the seizure threshold
c- Sedation
d- Constipation
i48- All of the following are clinical applications of desmopressin except :i
a- Diabetes Insipidus
b- Nocturnal eneuresis
c- Urinary retention
d- Post operative poly urea
a- Diabetes Insipidus
b- Nocturnal eneuresis
c- Urinary retention
d- Post operative poly urea
[b]i49- All of the following have very limited crossing through inflamed meninges except :i
a- Clavulanic acid salts
b- Penicillin
c- Teicoplanin
d- Erythromycin
a- Clavulanic acid salts
b- Penicillin
c- Teicoplanin
d- Erythromycin
i50- All of the following are mainly Bacteriostatics except :i
a- Chloramphenicol
b- Sulphadiazine
c- Ampicillin
d- Tetracycline
a- Chloramphenicol
b- Sulphadiazine
c- Ampicillin
d- Tetracycline
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