i1- Wich of th following is not a major pathway or type of biotransformations ?i
a- Oxidation
b- Deamination
c- Reduction
d- Hydrolysis
e- Conjugation


i2- Which of the following is not a naturally occurring emulsifier?i
a- Acacia
b- Cholesterol
c- Gelatine
d- Veegum
e- Tragacanth


i3- Which of the following symptoms is not present in digitalis intoxication?i
a- AV block
b- Ventricular tachycardia
c- Vomiting
d- Vagal arrest of the heart
e- Visual disturbances


i4- Which of the following statements about propylthiouracil is false ?i
a- It is used for treatment of hyperthyroidism
b- It inhibits the synthesis of thyroid hormones
c- It diminishes peripheral deiodination of T4 and T3
d- It inhibits iodide oxidation
e- It interferes with the effectiveness of exogenously administered thyroid hormones


i5- All of the following are diuretics except :i
a- Aminophylline
b- Glyburide
c- Spironolactone
d- Bum etamide
e- Chlorthalidone


i6- Which of the following is not a side effect of codeine?i
a- Miosis
b- Nausea
c- Diarrhea
d- Respiratory depression
e- Addiction


i7- All of the following are natural estrogens or congeners except :i
a- Estradiol
b- Diethylstilbestrol
c- Estrone
d- Ethinyl estradiol
e- Estropipate


i8- Epinephrine is not given orally because :i
a- It is inactivated in the gastric mucosa
b- Local vasoconstriction inhibits absorption
c- It is raoidly inactivated in circulation
d- None of the above
e- All of the above


i9- Wich of the following cardiac glycosides does not occur naturally ?i
a- Dogoxin
b- Oubain
c- Digitoxin
d- Amrinone
e- Nitroglycerin


i10- Various opiates may be used as all of the following except :i
a- Analgesics
b- Anti-inflammatories
c- Antidiarreals
d- Aids to anesthesia
e- Antitussive







i11- Which of the following is not a stimulant laxative ?i
a- Cascara Sagrada
b- Senna
c- Caster oil
d- Bisacodyl
e- Docsate


i12- Which of the following action is not seen with sympathomimetics ?i
a- Pupil constriction
b- Increased heart rate
c- Sweat gland stimulation
d- Bronchiole dilation
e- Systemic blood vessel constriction


i13- All of the following statements about propranolol are true except :i
a- The oral route of administration is preferred
b- Propranolol penetratesin to the CNS
c- Propranolol is primarily biotransformed in the liver
d- Propranolol causes rashes and sore throut
e- It is non selective alpha antagonist


i14- Which of the following drugs is not a proton pump inhibitor ?i
a- Pantoprazole
b- Rabeprazole
c- Lansoprazole
d- Sulfisoxazole
e- Omeprazole


i15- All of the following are side effects of progestins except :i
a- Weight gain
b- Headache
c- Fatigue
d- Constipation
e- Nausea and vomiting


i16-Bacitarcin is not usually given parenterally because of its :i
a- Insolubility
b- Lack of stability
c- Pain at the injection site
d- Lack of potency
e- Nephrotoxicity


i17- Which of the following drugs should not be administered with high fat meals ?i
i|. Indinazir
i||. Riluzole
i|||. Stavudine


a- | only
b- ||| only
c- | and || only
d- || and ||| only
e- | , || and |||i


i18- Each of the following exert antimicrobial action by inhibiting cell wall synthesis except :i
a- Cephalosporins
b- Penicillin
c- Bacitracin
d- Vancomycin
e- Novobiocin


i19- Which of the following antibiotics or group of antibiotics does not act by inhibiting of cell membrane function ?i
a- Erythromycin
b- Amphotericin B
c- Colistin
d- Nystatin
e- Polymyxins


i20-Which of the following diuretics do not cause potassium loss ?i
a- Furosemide
b- Chlorthalidone
c- Triamterene
d- Hydrochlorothiazide
e- Metolazole
i21- Which is not essential amino acid ?i
a- Threonine
b- Tryptophane
c- Glutamone
d- Methionine


i22- Hypercalcemia does not occur in normal individuals because :i
a- Calcium is rapidly excreted
b- Calcium is rapidly biotransformed
c- Calcium is insoluble
d- Excess calcium is not absorbed


i23- All of the following are true of haemolytic jaundice except :i
a- There is increased production of Bilirubin
b- Urobilinogin concentration is increased in urine
c- Production of Urobilinogin is increased
d- Bilirubin is found in the urine of the patient
e- None of the above because all are true


i24- Which of the following beta-adrenergic agents is not short acting ?i
a- Pirbuterol
b- Salmetrol
c- Terbutaline
d- Albuterol
e- None of the above


i25- Possible treatment of Hypoglycemia does not include :i
a- Insulin
b- Candy
c- Glucose
d- Fruit juce
e- Glucagon


i26- Which of the following Antihypertensive agents has no adverse effect on Glucose tolerance?i
i1-metoprolol
i2-atenolol
i3-captopril


ia. 1 only
ib. 3 only
ic. 1 and 2i
id. 2 and 3i
ie. 1 , 2 and 3 i


i27- Signs and symptoms of acute Otitis media do not include :i
a- Fever
b- Irritability
c- Stuff neck
d- Lethargy
e- The child may be as asymptomatic


i28- Alternative Antibiotics for Otitis media for the child allergic to Penicillin include all of the following except :i
a- Clindamycin
b- Erythromycin
c- Erythromycin – Sulfisoxazole
d- Ciprofloxacin
e- Trimethoprin – Sulfamethoxazole


i29- It is important that the patient recognizes all the following signs as possible Lithium side effects except :i
a- Hand tremors
b- Headaches
c- Mudcle weakness
d- Constipation
e- Polyuria


i30- Which of the following is not useful in the treatment of acute Digoxin toxicity ?i
i1- calcium administration
i2- lidocaine administration
i3- fab fragment antibodies


ia. 1 only
ib. 3only
ic. 1 and 2 only
id. 2 and 3 only
ie. 1 , 2 and 3


i31- Some common patient complaints associated with Anticholinergic drugs include all of the following except :i
a- Urinary retention
b- Sgortness of breath
c- Blurred vision
d- Constipation
e- Dry mouth

i32- Which of the following iron preparations is not available oral dosage form ?i
a- Iron drxtran
b- Ferrous fumarate
c- Ferrous gluconate
d- Ferrous sulphate
e- Polysaccharide – Iron complex


i33- In which of the following conditions is iron supplementation indicated ?i
i1 Primary hemochromatosis
i2 Patient receiving multiple blood transfusions
i3 Pregnancy


a- 1 only
b- 3 Only
c- 1 and 2 only
d- 1, 2 and 3


i34- Some symptoms of iron deficiency include all of the following except :i
a- Fatigue
b- Constant thirst
c- Dystrophy of nails
d- Dysphagia
e- Dispnea on exertion


i35- Which of the following agents would not be indicated for a patient with angina ?i
a- Isosorbide
b- Flecainide
c- Nifedipine
d- Inderal
e- Diltiazem


i36- All of the following may be symptoms of a myocardial infarction except :i
a- Myalgia, Mydriasis and Nocturia
b- Agitated behavior and ahen pallor
c- Nausea, sweating and dyspnea
d- Heartburn, fainting and skipped beats
e- Dental and neck pain, no relief from Nitroglycerin


i37- All of the following are true about morphine except :i
a- May cause diarhoea
b- A m etabolite of codeine
c- Has specific receptors in the GIT
d- May cause vomiting


i38- Which one of the following drugs is not available as antipsychotic depot injection ?i
a- Flupenthixol
b- Fluphenazine
c- Chlorpromazine HCL
d- Haloperidol Decanoate


i39- Which one of the following statements about chloral hydrate is false ?i
a- May cause gastritis
b- Can cause tolerance
c- It is a respiratory stimulant
d- Toxicity is much increased by administration of Ethanol


i40- Which one of the following statements about narcotic analgesics is false ?i
a- Codeine is useful for its anti tussive properties
b- Pentazocine is more addictive than morphine
c- Pentazocine may cause hallucinations
d- Morphine can cause diarhoea






i41- Which of the following should not be used to prevent migraine in an asthmatic patient ?i
a- Propranolol (Inderal)i
b- Pizotifen (Sanomigran)i
c- Amitryptyline (Tryptizol)i
d- Clonidine (Dixarit)i


i42- Which of the following is not a benzodiazepine ?i
a- Alprazolam
b- Clobazem
c- Chlormethiazole
d- Chlordiazepoxide


i43- Which of the following is true about Benzodiazepines ?i
a- Patients can develop a psychological dependence
b- Patients can develop a withdrawal syndrome
c- Patients can develop tolerance to the drug
d- All of the above


i44- Dopamine tablets cannot be used to treat Parkinson’s disease because it :i
a- Does not cross blood brain barrier
b- Is too toxic after long term administration
c- Is transformed to L-dopa by the autonomic neurons
d- Is not m etabolized by mono amine oxidase


i45- Which of the following drugs cause insomnia ?i
a- MAOI’s
b- Caffeine
c- Beta blockers
d- Barbiturates
e- a, b and c


i46- Which of the following is not effective for partial seizures ?i
a- Phenytoin
b- Ethosuximide
c- Carbamazepine
d- Lamotrigine


i47- Amitryptyline causes all of the following except :i
a- Hypotension in the elderly
b- Raising of the seizure threshold
c- Sedation
d- Constipation


i48- All of the following are clinical applications of desmopressin except :i
a- Diabetes Insipidus
b- Nocturnal eneuresis
c- Urinary retention
d- Post operative poly urea


[b]i49- All of the following have very limited crossing through inflamed meninges except :i
a- Clavulanic acid salts
b- Penicillin
c- Teicoplanin
d- Erythromycin


i50- All of the following are mainly Bacteriostatics except :i
a- Chloramphenicol
b- Sulphadiazine
c- Ampicillin
d- Tetracycline




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