ALZENTAL
Composition
Suspension
(1ml) 1 Tablet
Albendazole 20 mg 200 mg
Properties and Mode of Action
ALZENTAL, a benzimidazole carbamate derivative, is an anthelmintic with activity against most nematode and some other worms. Activity against some larval stages and ova has also been demonstrated.
ALZENTAL’s anthelmintic activity is considered to be dependent on the inhibition or destruction of cytoplasmic microtubules in the worm’s intestinal or absorptive cells. Inhibition of glucose uptake and depletion of glycogen stores follow as do other inhibitory effects Ieading to death of the worm.
Indications
ALZENTAL is a broad spectrum anthelmintic used in the treatmemt of single and mixed infections as:
Enterobiasis
Ascariasis
Hookworms
Trichuriasis
Strongyloidiasis
Taeniasis Capillariasis
Cysticercosis
Toxocariasis
Trichostrongyliasis
Trichinosis
Echinococcosis (Hydatid disease)
Dosage and Administration
Adults and Children Above 2 years of age:
Enterobiasis, Ascariasis, Hookworm, Trichuriasis:
400 mg as a single dose.
Treatment may be repeated in 3 weeks.
Cysticercosis:
15 mg/kg body weight/day for 30 days.
Strongyloidiasis and Taeniasis:
400 mg is given daily for 3 consecutive days.
This may be repeated after 3 weeks if necessary.
Capillariasis:
200 mg twice daily for 10 days.
Echinococcosis (Hydatid disease):
(Over 60 kg body weight): 800 mg/day in divided doses for 28 days.
This is followed by 2 weeks drug free interval, to be repeated for 2-3 cycles.
For inoperable cases up to 5 cycles may be given.
(Under 60 kg body weight): 10-15 mg/kg body weight daily for 28 days.
Children Up to 2 years of age:
Enterobiasis, Ascariasis, Hookworm, Trichuriasis:
200 mg as a single dose.
Treatment may be repeated in 3 weeks.
Precautions
ALZENTAL may cause elevation in hepatic enzymes.
Patients receiving high doses of ALZENTAL, such as those with Hydatid disease, should be supervised closely with blood counts and liver function being monitored.
Contra_indications
Pregnancy.
Hypersensitivity to Albendazole.
Side effects
Incidence is rare and reversible: e.g.nausea, vomiting, diarrhoea, leucopenia, elevated transaminases.
Presentation
ALZENTAL Suspension :Bottle of 20 ml.
ALZENTAL Tablets : Box of 1 blister of 2 tablets.
Composition
Suspension
(1ml) 1 Tablet
Albendazole 20 mg 200 mg
Properties and Mode of Action
ALZENTAL, a benzimidazole carbamate derivative, is an anthelmintic with activity against most nematode and some other worms. Activity against some larval stages and ova has also been demonstrated.
ALZENTAL’s anthelmintic activity is considered to be dependent on the inhibition or destruction of cytoplasmic microtubules in the worm’s intestinal or absorptive cells. Inhibition of glucose uptake and depletion of glycogen stores follow as do other inhibitory effects Ieading to death of the worm.
Indications
ALZENTAL is a broad spectrum anthelmintic used in the treatmemt of single and mixed infections as:
Enterobiasis
Ascariasis
Hookworms
Trichuriasis
Strongyloidiasis
Taeniasis Capillariasis
Cysticercosis
Toxocariasis
Trichostrongyliasis
Trichinosis
Echinococcosis (Hydatid disease)
Dosage and Administration
Adults and Children Above 2 years of age:
Enterobiasis, Ascariasis, Hookworm, Trichuriasis:
400 mg as a single dose.
Treatment may be repeated in 3 weeks.
Cysticercosis:
15 mg/kg body weight/day for 30 days.
Strongyloidiasis and Taeniasis:
400 mg is given daily for 3 consecutive days.
This may be repeated after 3 weeks if necessary.
Capillariasis:
200 mg twice daily for 10 days.
Echinococcosis (Hydatid disease):
(Over 60 kg body weight): 800 mg/day in divided doses for 28 days.
This is followed by 2 weeks drug free interval, to be repeated for 2-3 cycles.
For inoperable cases up to 5 cycles may be given.
(Under 60 kg body weight): 10-15 mg/kg body weight daily for 28 days.
Children Up to 2 years of age:
Enterobiasis, Ascariasis, Hookworm, Trichuriasis:
200 mg as a single dose.
Treatment may be repeated in 3 weeks.
Precautions
ALZENTAL may cause elevation in hepatic enzymes.
Patients receiving high doses of ALZENTAL, such as those with Hydatid disease, should be supervised closely with blood counts and liver function being monitored.
Contra_indications
Pregnancy.
Hypersensitivity to Albendazole.
Side effects
Incidence is rare and reversible: e.g.nausea, vomiting, diarrhoea, leucopenia, elevated transaminases.
Presentation
ALZENTAL Suspension :Bottle of 20 ml.
ALZENTAL Tablets : Box of 1 blister of 2 tablets.